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Thalix-50 contains thalidomide and belongs to a class of medications called immunomodulatory agents.


Thalix-50 contains thalidomide and belongs to a class of medications called immunomodulatory agents.


Thalix is used in combination with dexamethasone to treat multiple myeloma in patients who have been newly diagnosed with this disease.

Thalix-50 is used alone or with other medications for treating and preventing skin inflammation in patients who have moderate to severe erythema nodosum leprosum (enl: episodes of skin sores, fever, and nerve damage that occur in people with hansen’s disease [leprosy]).


Should be taken on an empty stomach. (Take on an empty stomach at least 1 hr after a meal, w/ a full glass of water.)
Adult: PO Erythema nodosum leprosum (Type 2) 100-300 mg at bedtime, reduce gradually once a satisfactory reponse is achieved. Max: 400 mg/day. Multiple myeloma Initial: 200 mg once daily, increase slowly according to patient tolerance. Max: 800 mg/day.

Warning & Precautions

Thalidomide enhances sedative activity of barbiturates, alcohol, chlorpromazine and reserpine. Avoid use of other drugs that have the potential to cause peripheral neuropathy. Increased risk of thromboembolic events with darbepoetin-alfa anddoxorubicin.
Potentially Fatal: Increased risk of bone marrow supression with peg interferon alfa.

Side Effects

Severe and irreversible peripheral neuropathy, constipation, dizziness, orthostatic hypotension, drowsiness, somnolence, bradycardia, increase of viral load in HIV-infected patients, hypersensitivity reaction.
Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis and blood dyscrasias.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed out of the reach of children.

Disclaimer We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment

Additional information

no of pills

30, 60, 90, 120, 150


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